Facioscapulohumeral muscular dystrophy (FSHD) is one of the most prevalent neuromuscular disorders. The disease is linked to copy number reduction and/or epigenetic alterations of the D4Z4 macrosatellite on chromosome 4q35 and associated with aberrant gain of expression of the transcription factor DUX4, which triggers a pro-apoptotic transcriptional program leading to muscle wasting. As today, no cure or therapeutic option is available to FSHD patients. Given its centrality in FSHD, blocking DUX4 expression with small molecule drugs is an attractive option.
Read original article and view video content here. Brooklyn Nets’ radio announcer Chris Carrino is being honored by the NBA for both his decades of work and the obstacles he has overcome. After more than 20 years as the radio play-by-play voice of the Nets, Carrino has been recognized by the NBA with “The Values …
Read more “Brooklyn Nets’ radio announcer Chris Carrino honored by NBA”
This article originally appeared on netsdaily.com. The NBA is honoring Chris Carrino, the play-by-play announcer, with the prestigious NBA Values of the Game Award this year, the Nets and the league reported Tuesday. The award recognizes an individual at an NBA team who exemplifies the values of the league in their community. The NBA is also honoring …
Read more “NBA honors Chris Carrino with ‘Values of the Game’ award”
https://youtu.be/LXr1L4NOmos
Justin Cohen is a remarkable young researcher, living with FSHD, and efforting to find a cure for the disease. The Carrino Foundation is proud to make his work possible. Here is Justin’s story, in his own words.
There are approximately 15 steps that Chris Carrino will need to navigate in order to reach his broadcast position inside Wells Fargo Center. It may not seem all that daunting, but a small flight of stairs is physically challenging and potentially dangerous for someone living with muscular dystrophy.
Fastfoward to the 18:45 minute mark to hear Chris’ interview.
This article originally appeared on app.com Jerry Carino , @njhoopshaven Published 5:02 a.m. ET May 18, 2017 | Updated 4:20 p.m. ET May 20, 2017 As the new co-director of a highly successful sports broadcasting camp for teens, Marlboro’s Chris Carrino draws on experiences beyond the basketball court. A few years …
Read more “Nets Broadcaster Is A Mentor With A Mission”
We are proud to announce that the Board of Directors of the Chris Carrino Foundation for FSHD has recently awarded a scientific research grant in the amount of $75,625 to Dr. Scott Harper and his team at The Ohio State University. The grant will fund a study titled “Developing a muscle-specific DUX4 inhibition system for …
Read more “Chris Carrino Foundation Board Awards Research Grant to Dr. Scott Harper at The Ohio State University”
